Download e-book for iPad: Alternative Toxicological Methods by Harry Salem,Sidney A. Katz

By Harry Salem,Sidney A. Katz

ISBN-10: 084931528X

ISBN-13: 9780849315282

Bringing jointly the hot and suitable contributions of over a hundred twenty five scientists from undefined, executive, and academia in North the United States and Western Europe, substitute Toxicological equipment explores the improvement and validation of substitute, relief, and refinement possible choices (the 3Rs) to animal checking out. the world over well-known scientists current what has been entire up to now in constructing appropriate choices to conventional animal toxicological review and supply in all likelihood new initiatives.

In over forty chapters, the ebook addresses 7 issues, starting with the validation and regulatory attractiveness of choices within the US, the united kingdom, and Western Europe. Then the ebook covers equipment according to the mechanisms of eye inflammation on the ocular floor, dermal toxicity checking out, and assessing neurotoxicity. it's also a case examine within the use of choices to figure out the mechanism of sulfur mustard motion and discusses the function of transgenics and toxicokinetics within the improvement of other toxicity checks. eventually the ebook provides fresh options in possible choices, together with using archival information, and in silico techniques.

Focusing at the technology and never the politics, substitute Toxicological tools concisely discusses the appliance of cutting-edge equipment and explores state-of-the-art study with regards to constructing and validating possible choices to animal trying out. This e-book will gain toxicologists, beauty chemists, pharmacologists, experimental biologists, dermatologists, ophthalmologists, and regulatory officials of their quest for making use of the 3Rs to using animals in toxicological trying out of drug applicants, chemical substances, and cosmetics.

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Alternative Toxicological Methods by Harry Salem,Sidney A. Katz

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